Newcastle is a principal stop on the East Coast Main Line.
East Coast trains run south to London Kings Cross via York, Doncaster and Peterborough and north to Edinburgh Waverley, Glasgow Central, Aberdeen and Inverness.
CrossCountry services run south to their Birmingham New Street hub via York, Leeds/Doncaster, Sheffield and Derby and onwards to Reading via Oxford; Plymouth or Penzance via Cheltenham Spa and Bristol Temple Meads; and north to Edinburgh, Glasgow and Aberdeen.
First TransPennine Express trains run to Manchester Airport and Liverpool Lime Street via York, Leeds, Huddersfield and Manchester Piccadilly.